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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apohtm1Krl
targeted mutation 1, Steven A Krilis
MGI:2157224
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apohtm1Krl/Apohtm1Krl involves: 129/Sv * C57BL/6 MGI:2655421


Genotype
MGI:2655421
hm1
Allelic
Composition		 Apohtm1Krl/Apohtm1Krl
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apohtm1Krl mutation (0 available); any Apoh mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:68990 )
• heterozygous intercross produces only 8.9% homozygous null mutants

homeostasis/metabolism
abnormal blood homeostasis ( J:68990 )
• mutants that are born show reduced in vitro thrombin production
• however, no differences in clotting times of plasma are observed




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory