reproductive system
|
• at 8 weeks of age the number of apoptotic male germ cells was 5 times the normal level, resulting in the testes losing 70% of their mass due to germ cell loss
|
azoospermia
(
J:50338
)
|
• cauda epididymides of mutant mice are devoid of sperm
|
|
• numerous degenerating cells are present, some in the form of symplasts, giant cells containing multiple degenerating nuclei
|
|
• Sertoli cell numbers are reduced to 16% of their normal level at 6 weeks of age
|
|
• small in diameter and often lack a lumen
|
endocrine/exocrine glands
|
• numerous degenerating cells are present, some in the form of symplasts, giant cells containing multiple degenerating nuclei
|
|
• Sertoli cell numbers are reduced to 16% of their normal level at 6 weeks of age
|
|
• small in diameter and often lack a lumen
|
cellular
azoospermia
(
J:50338
)
|
• cauda epididymides of mutant mice are devoid of sperm
|
|
• at 8 weeks of age the number of apoptotic male germ cells was 5 times the normal level, resulting in the testes losing 70% of their mass due to germ cell loss
|