All Phenotypes Npy1r<tm1Pern> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Npy1r^tm1Pern
targeted mutation 1, Patrik Ernfors
MGI:2158704

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Npy1r^tm1Pern/Npy1r^tm1Pern	Not Specified	MGI:3763742
cx2	Npy1r^tm1Pern/Npy1r^tm1Pern Npy2r^tm1Pern/Npy2r^tm1Pern	involves: 129	MGI:3763741

Allelic Composition	Npy1r^tm1Pern/Npy1r^tm1Pern
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npy1r^tm1Pern mutation (1 available); any Npy1r mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal righting response ( J:71826 )

• loss of righting response following injection of pentobarbital or ketamin is reduced compared to in wild-type mice

Allelic Composition	Npy1r^tm1Pern/Npy1r^tm1Pern Npy2r^tm1Pern/Npy2r^tm1Pern
Genetic Background	involves: 129

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npy1r^tm1Pern mutation (1 available); any Npy1r mutation (25 available)
Npy2r^tm1Pern mutation (1 available); any Npy2r mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal righting response ( J:71826 )

• authors state that mice display a similar sensitivity to loss of righting response induced by pentobarbital as Npy1r^tm1Pern homozygous mice

• mice display a decrease in loss of righting response to ketamin-sedation compared to wild-type mice

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