Phenotypes associated with this allele

• Allele Symbol: Ptprs^tm1Dro
• Allele Name: targeted mutation 1, Daniela Rotin
• Allele ID: MGI:2158734
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptprs^tm1Dro/Ptprs^tm1Dro	involves: 129	MGI:3622892

Genotype
MGI:3622892

hm1

• Allelic Composition: Ptprs^tm1Dro/Ptprs^tm1Dro
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:107835 )

• majority of homozygotes (60%) die within hours of birth; 37.5% die due to a wasting syndrome by 2-3 weeks of age while 2.5% survive to adulthood, appearing healthy

growth/size/body

cachexia ( J:107835 )

• 37.5% of neonates demonstrate a wasting syndrome and die by 2-3 weeks of age

postnatal growth retardation ( J:107835 )

• 37.5% of neonates exhibit growth retardation and die by 2-3 weeks of age