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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(HLA-B27)30-4Trg
transgene insertion 30-4, Joel D Taurog
MGI:2159095
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(HLA-B27)30-4Trg/? involves: C57BL/6J * NOD MGI:3723605


Genotype
MGI:3723605
tg1
Allelic
Composition		 Tg(HLA-B27)30-4Trg/?
Genetic
Background		 involves: C57BL/6J * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(HLA-B27)30-4Trg mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to autoimmune diabetes ( J:109851 )
• mice are significantly protected from diabetes, with an incidence of 5/14 diabetic females at 30 weeks compared to 19/20 non-transgenic controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory