All Phenotypes Inpp5b<tm2.1Nbm> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Inpp5b^tm2.1Nbm
targeted mutation 2.1, Robert L Nussbaum
MGI:2159620

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Inpp5b^tm2.1Nbm/Inpp5b^tm2.1Nbm	involves: 129S6/SvEvTac * FVB/N	MGI:3040922

Allelic Composition	Inpp5b^tm2.1Nbm/Inpp5b^tm2.1Nbm
Genetic Background	involves: 129S6/SvEvTac * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Inpp5b^tm2.1Nbm mutation (0 available); any Inpp5b mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:73678 )

• about half of the males on a mixed 129S6/SvEvTac and FVB/N background are infertile

• infertile males are unable to process Adam2 while males with reduced fertility are able to process Adam2

reduced male fertility ( J:73678 )

• about half of the males on a mixed 129S6/SvEvTac and FVB/N background are fertile but sire smaller than normal litters

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24