Phenotypes associated with this allele

• Allele Symbol: Kif5b^tm1Noh
• Allele Name: targeted mutation 1, Nobutaka Hirokawa
• Allele ID: MGI:2159694
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kif5b^tm1Noh/Kif5b^tm1Noh	involves: 129S4/SvJae * C57BL/6J	MGI:3583004

Genotype
MGI:3583004

hm1

• Allelic Composition: Kif5b^tm1Noh/Kif5b^tm1Noh
• Genetic Background: involves: 129S4/SvJae * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:48447 )

• death occurred between E9.5 and E11.5 but embryos were unturned at last observation

embryo

abnormal embryo turning ( J:48447 )

• embryo turning has not occurred at E9.5

decreased embryo size ( J:48447 )

• severe growth retardation at E9.5 as determined by crown to rump lengths

cellular

abnormal mitochondrial morphology ( J:48447 )

• mitochondria clustered perinuclearly and anchored to microtubules

abnormal lysosome morphology ( J:48447 )

• tended to be more clustered than in controls

growth/size/body

decreased embryo size ( J:48447 )

• severe growth retardation at E9.5 as determined by crown to rump lengths