Phenotypes associated with this allele

• Allele Symbol: Crygc^Chl3
• Allele Name: chlorambucil, exon 3
• Allele ID: MGI:2176919
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crygc^Chl3/Crygc^Chl3	involves: 102/El * C3H/El	MGI:2176927
ht2	Crygc^Chl3/Crygc^+	involves: 102/El * C3H/El	MGI:2176925

Genotype
MGI:2176927

hm1

• Allelic Composition: Crygc^Chl3/Crygc^Chl3
• Genetic Background: involves: 102/El * C3H/El

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

cataract ( J:73804 )

• altered core of the lens with degenerated embryonic primary fiber cells

• bilateral nuclear and radial cataracts

• presence of cell nuclei throughout the entire lens

microphthalmia ( J:73804 )

• slight microphthalmia

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 2 multiple types		DOID:0110235	OMIM:604307	J:73804

Genotype
MGI:2176925

ht2

• Allelic Composition: Crygc^Chl3/Crygc⁺
• Genetic Background: involves: 102/El * C3H/El

vision/eye

cataract ( J:73804 )

• bilateral nuclear and radial cataracts, less severe than homozygote

• presence of cell nuclei throughout the entire lens

• altered core of the lens with degenerated embryonic primary fiber cells

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 2 multiple types		DOID:0110235	OMIM:604307	J:73804