About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mei1m1Jcs
mutation 1, John C Schimenti
MGI:2176973
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mei1m1Jcs/Mei1m1Jcs involves: 129S1/Sv MGI:5490541
hm2
Mei1m1Jcs/Mei1m1Jcs involves: 129S1/Sv * C57BL/6J MGI:2177040


Genotype
MGI:5490541
hm1
Allelic
Composition
Mei1m1Jcs/Mei1m1Jcs
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mei1m1Jcs mutation (1 available); any Mei1 mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• male germ cells lack double strand break
• however, pre-prophase pairing is normal

cellular
• male germ cells lack double strand break
• however, pre-prophase pairing is normal




Genotype
MGI:2177040
hm2
Allelic
Composition
Mei1m1Jcs/Mei1m1Jcs
Genetic
Background
involves: 129S1/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mei1m1Jcs mutation (1 available); any Mei1 mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• absent sperm, absence of post-meiotic cells
• meiotic defects
• spermatocytes arrest at zygotene stage of meiosis I

endocrine/exocrine glands

cellular
• absent sperm, absence of post-meiotic cells
• meiotic defects
• spermatocytes arrest at zygotene stage of meiosis I





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory