Analysis Tools
growth/size/body
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• mutants on a potassium-free diet lose weight more rapidly than wild-type, showing a 20% decrease in body weight after 18 days of potassium depletion
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• slight increase in kidney weight after 18 days on a potassium-free diet
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renal/urinary system
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• slight increase in kidney weight after 18 days on a potassium-free diet
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• on a normal diet, fecal potassium excretion is twice that of wild-type mice
• on a potassium-free diet, mutants exhibit a smaller reduction in fecal potassium excretion (4.5-fold) compared to wild-type (7-fold)
• due to increased loss of potassium in the colon, mutants on a potassium-free diet exhibit lower muscle potassium levels than wild-type
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digestive/alimentary system
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• on a normal diet, fecal potassium excretion is twice that of wild-type mice
• on a potassium-free diet, mutants exhibit a smaller reduction in fecal potassium excretion (4.5-fold) compared to wild-type (7-fold)
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homeostasis/metabolism
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• on a potassium-free diet, mutants exhibit reduced plasma potassium levels compared to wild-type
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• on a normal diet, fecal potassium excretion is twice that of wild-type mice
• on a potassium-free diet, mutants exhibit a smaller reduction in fecal potassium excretion (4.5-fold) compared to wild-type (7-fold)
• due to increased loss of potassium in the colon, mutants on a potassium-free diet exhibit lower muscle potassium levels than wild-type
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