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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tcf3tm2Wein
targeted mutation 1, Harold Weintraub
MGI:2178116
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tcf3tm2Wein/Tcf3tm2Wein Not Specified MGI:3776843


Genotype
MGI:3776843
hm1
Allelic
Composition		 Tcf3tm2Wein/Tcf3tm2Wein
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf3tm2Wein mutation (0 available); any Tcf3 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:47671 )
• authors state that the phenotype is essentially the same as in Tcfe2atm1Wein homozygotes
postnatal lethality ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes

reproductive system
female infertility ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes

immune system
abnormal immune system morphology ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes
increased T cell derived lymphoma incidence ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes

neoplasm
increased T cell derived lymphoma incidence ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes

growth/size/body
postnatal growth retardation ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes

hematopoietic system
abnormal hematopoietic system morphology/development ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes
increased T cell derived lymphoma incidence ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:47671 )
• authors state that the pehnotype is essentially the same as in Tcfe2atm1Wein homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory