Phenotypes associated with this allele

• Allele Symbol: Lrp1^tm1Her
• Allele Name: targeted mutation 1, Joachim Herz
• Allele ID: MGI:2178192
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrp1^tm1Her/Lrp1^tm1Her	involves: 129S7/SvEvBrd	MGI:2180889

Genotype
MGI:2180889

hm1

• Allelic Composition: Lrp1^tm1Her/Lrp1^tm1Her
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:30077 )

• fewer than expected mice are found at E10.5

• all mice are dead by E13.5

embryo

embryonic growth retardation ( J:30077 )

• some mice exhibit growth arrest or retardation at E9.5 and E10.5

cardiovascular system

internal hemorrhage ( J:30077 )

• in some mice at E10.5 and E13.5

growth/size/body

embryonic growth retardation ( J:30077 )

• some mice exhibit growth arrest or retardation at E9.5 and E10.5