Phenotypes associated with this allele

• Allele Symbol: Myc^{tm1.1(Nmyc1)Fwa}
• Allele Name: targeted mutation 1.1, Frederick W Alt
• Allele ID: MGI:2178232
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myc^tm1.1(Nmyc1)Fwa/Myc^tm1.1(Nmyc1)Fwa	involves: 129P2/OlaHsd * C57BL/6	MGI:2182118

Genotype
MGI:2182118

hm1

• Allelic Composition: Myc^{tm1.1(Nmyc1)Fwa}/Myc^{tm1.1(Nmyc1)Fwa}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:62573 )

• a fraction of mutants die within the first two days of life

muscle

abnormal skeletal muscle morphology ( J:62573 )

• about half of newborns exhibit dystrophy of skeletal muscles

growth/size/body

decreased birth body size ( J:62573 )

• newborns are slightly smaller in size than controls

decreased birth weight ( J:62573 )

• newborns weight slightly less than controls

decreased body size ( J:62573 )

• adults are slightly smaller in size than controls

decreased body weight ( J:62573 )

• adults weight slightly less than controls

homeostasis/metabolism

cyanosis ( J:62573 )

• two neonates exhibit cyanosis

immune system

immune system phenotype ( J:62573 )

N • lymphocyte development and mitogen responses of lymphocytes are normal