Phenotypes associated with this allele

• Allele Symbol: Col4a1^Svc
• Allele Name: small with vacuolar cataract
• Allele ID: MGI:2178448
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Col4a1^Svc/Col4a1^+	involves: BALB/cAnN * C3H/HeN	MGI:3028512

Genotype
MGI:3028512

ht1

• Allelic Composition: Col4a1^Svc/Col4a1⁺
• Genetic Background: involves: BALB/cAnN * C3H/HeN

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:75964 )

• mice were small at birth

vision/eye

irregularly shaped pupil ( J:75964 )

abnormal cornea morphology ( J:75964 )

anterior iris synechia ( J:75964 )

• peripheral iris-corneal adhesion

cornea opacity ( J:75964 )

• corneal opacity and ectasia

anterior subcapsular cataract ( J:75964 )

• the most consistent eye defect observed in these mice, gave a vacuolar appearance to the lens although some mutants showed anterior subcapsular cataracts

buphthalmos ( J:75964 )

• possibly due to glaucoma

abnormal retina morphology ( J:75964 )

• shiny appearance to retinal arterioles

vitreal fibroplasia ( J:75964 )

• in a few mice, a fibrovascular tuft is present in the vitreous

cardiovascular system

bruising ( J:75964 )

• mice had a bruised appearance at birth