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Allele Symbol Allele Name Allele ID |
Nlrp5tm1Zbt targeted mutation 1, Zhi-Bin Tong MGI:2178449 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• zygotes lack a fine meshwork of cytoplasmic F-actin resulting in acentric spindle position
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• no embryos derived from homozygous mothers developed past the 2-cell stage, however maternal folliculogenesis, corpora lutea, and the oestrus cycle are normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• fewer than 2% of embryos from homozygous females progress beyond the 2 cell stage
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• zygotes exhibit mitotic spindle that are dysmorphic, smaller and displaced from the cell center
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• asymmetric division
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/15/2024 MGI 6.24 |
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