cellular
N |
• fibroblasts exhibit normal nucleotide excision repair, repair of alkylation damage, sensitivity to 3-aminobenzamide, repair of ionizing radiation damage, and sister chromatid exchange rates
|
• cultured fibroblasts grow more slowly than wild-type cells
|
• fibroblasts accumulate replication intermediates unlike in wild-type cells
|
• fibroblasts exhibit increased chromosomal instability compared to wild-type cells
|
hematopoietic system
• when fetal liver cells are used to rescue lethally irradiated mice
|
• when fetal liver cells are used to rescue lethally irradiated mice, fetal liver cells contribute to all lineages but in lower numbers than when wild-type cells are used to rescue lethally irradiated mice
|
• when fetal liver cells are used to rescue lethally irradiated mice
|
• when fetal liver cells are used to rescue lethally irradiated mice
|
macrocytosis
(
J:75962
)
• when fetal liver cells are used to rescue lethally irradiated mice
|
• when fetal liver cells are used to rescue lethally irradiated mice
|
homeostasis/metabolism
• fibroblasts accumulate replication intermediates unlike in wild-type cells
|
immune system
• when fetal liver cells are used to rescue lethally irradiated mice
|
growth/size/body
• when fetal liver cells are used to rescue lethally irradiated mice
|