homeostasis/metabolism
• after middle cerebral artery occlusion induced infarction cerebral blood flow in the non-ischemic contralateral hemisphere is increased compared to wild-type controls
|
• following 90 min of ischemia induced by middle cerebral artery occlusion and 22.5 h of reperfusion infarct size is significantly larger in mutant males compared to wild-type male controls
• however, no differences in cerebral blood flow in the ischemic hemisphere before, during or after occlusion are detected
|
nervous system
• following 90 min of ischemia induced by middle cerebral artery occlusion and 22.5 h of reperfusion infarct size is significantly larger in mutant males compared to wild-type male controls
• however, no differences in cerebral blood flow in the ischemic hemisphere before, during or after occlusion are detected
|
behavior/neurological
• in a Morris water maze mice show longer escape latencies on each day of testing
|