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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Graptm1Gsf
targeted mutation 1, Gen-Sheng Feng
MGI:2179974
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Graptm1Gsf/Graptm1Gsf B6.129-Graptm1Gsf MGI:3639340


Genotype
MGI:3639340
hm1
Allelic
Composition		 Graptm1Gsf/Graptm1Gsf
Genetic
Background		 B6.129-Graptm1Gsf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Graptm1Gsf mutation (0 available); any Grap mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased T cell proliferation ( J:76243 )
• increased proliferative response to TCR stimulation
increased CD4-positive, alpha-beta T cell number ( J:76243 )
• slight increase in CD4 single positive T cells in the thymus but not in the periphery

hematopoietic system
increased T cell proliferation ( J:76243 )
• increased proliferative response to TCR stimulation
increased CD4-positive, alpha-beta T cell number ( J:76243 )
• slight increase in CD4 single positive T cells in the thymus but not in the periphery

cellular
increased T cell proliferation ( J:76243 )
• increased proliferative response to TCR stimulation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory