All Phenotypes Cacng1<tm1Vfz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cacng1^tm1Vfz
targeted mutation 1, Veit Flockerzi
MGI:2180153

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cacng1^tm1Vfz/Cacng1^tm1Vfz	involves: 129S1/Sv * 129X1/SvJ	MGI:2181797

Allelic Composition	Cacng1^tm1Vfz/Cacng1^tm1Vfz
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacng1^tm1Vfz mutation (0 available); any Cacng1 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal muscle electrophysiology ( J:62133 )

• peak calcium current amplitudes in skeletal muscle myotubes are increased, the time-dependent inactivation of calcium currents id decelerated and the steady state inactivation is shifted to more positive potentials, resulting in increased calcium influx through L-type calcium channels in myotubes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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