Phenotypes associated with this allele

• Allele Symbol: Galt^tm1Sgl
• Allele Name: targeted mutation 1, Stanton Segal
• Allele ID: MGI:2180188
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Galt^tm1Sgl/Galt^tm1Sgl	involves: 129P2/OlaHsd * CF-1	MGI:3640959

Genotype
MGI:3640959

hm1

• Allelic Composition: Galt^tm1Sgl/Galt^tm1Sgl
• Genetic Background: involves: 129P2/OlaHsd * CF-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal galactose homeostasis ( J:37472 , J:76729 )

• plasma levels of galactose substantially elevated (J:37472)

• galactose-1-phosphate elevated in the liver and in erythrocytes (J:37472)

• ability to oxidize dietary galactose increases 63% from suckling mice to 7 week old mice but remains about 1/3 of the rate seen in controls (J:76729)

• galactose-1-phosphate also elevated in the brain and kidney (J:76729)