About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd3dtm1Kap
targeted mutation 1, Dietmar J Kappes
MGI:2180760
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd3dtm1Kap/Cd3dtm1Kap C57BL/6-Cd3dtm1Kap MGI:2651579


Genotype
MGI:2651579
hm1
Allelic
Composition		 Cd3dtm1Kap/Cd3dtm1Kap
Genetic
Background		 C57BL/6-Cd3dtm1Kap
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd3dtm1Kap mutation (0 available); any Cd3d mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
arrested T cell differentiation ( J:39925 )
• block in alpha-beta T cell development; thymic selection is blocked at the transition from the double-positive to single-positive stages of development
• however, development of gamma-delta T cells is normal

hematopoietic system
arrested T cell differentiation ( J:39925 )
• block in alpha-beta T cell development; thymic selection is blocked at the transition from the double-positive to single-positive stages of development
• however, development of gamma-delta T cells is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory