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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mthfd2tm1Rmk
targeted mutation 1, Robert E MacKenzie
MGI:2180800
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mthfd2tm1Rmk/Mthfd2tm1Rmk involves: 129S1/Sv * 129X1/SvJ * BALB/c MGI:3574958


Genotype
MGI:3574958
hm1
Allelic
Composition		 Mthfd2tm1Rmk/Mthfd2tm1Rmk
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mthfd2tm1Rmk mutation (1 available); any Mthfd2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, complete penetrance ( J:76786 )
• most dead after E13.5, all embryos dead by E15.5

embryo

growth/size/body
decreased embryo size ( J:76786 )

liver/biliary system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory