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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Eci1tm1Wst
targeted mutation 1, Wilhelm Stoffel
MGI:2180887
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Eci1tm1Wst/Eci1tm1Wst involves: 129S1/Sv * 129X1/SvJ MGI:3694344


Genotype
MGI:3694344
hm1
Allelic
Composition
Eci1tm1Wst/Eci1tm1Wst
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eci1tm1Wst mutation (0 available); any Eci1 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• accumulation of unsaturated fatty acids in the liver and kidney after 48 hour starvation
• ratio of triglycerides to cholesterol in the liver and kidneys increased after 48 hours starvation rather than declining as in controls
• increased levels of fatty acid metabolites in the urine relative to controls
• levels of fatty acid metabolites in urine become vastly increased after starvation

renal/urinary system
• increased levels of fatty acid metabolites in the urine relative to controls
• levels of fatty acid metabolites in urine become vastly increased after starvation





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory