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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cntftm1Gdy
targeted mutation 1, George D Yancopoulos
MGI:2181048
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cntftm1Gdy/Cntftm1Gdy involves: 129P2/OlaHsd * C57BL/6 MGI:3618320


Genotype
MGI:3618320
hm1
Allelic
Composition		 Cntftm1Gdy/Cntftm1Gdy
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntftm1Gdy mutation (0 available); any Cntf mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:29357 )
N
• homozygous mice do not exhibit motor neuron deficits at birth, however later stages were not analyzed
abnormal motor neuron morphology ( J:66057 )
• motorneuron sprouting is not observed as in wild-type following partial muscle denervation or botulinum toxin induced paralysis at 2 and 8 months of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory