cardiovascular system
hypertension
(
J:59336
)
• slight increase in systolic blood pressure at rest
|
reproductive system
azoospermia
(
J:59336
)
|
• sperm was undetected in uterine lavage after matings with mutant males
• abundant motile sperm were detected in the vas deferens and epididymis
|
|
• impaired neurogenic vas deferens contraction
|
• mean litter size reduced by 30%
|
|
• fertility reduced by ~90%
|
cellular
azoospermia
(
J:59336
)
|
• sperm was undetected in uterine lavage after matings with mutant males
• abundant motile sperm were detected in the vas deferens and epididymis
|