respiratory system
• calcification of the alveoli is detected at 120 weeks of age
|
skeleton
cardiovascular system
• blood flow restoration and capillary growth are impaired following induced hindlimb ischemia
|
homeostasis/metabolism
• the pancreatic insulin content of 8 week old heterozygotes is approximately 118 ug/g, lower than the 171 mg/g in wildtype controls and higher than the 34 mg/g in homozygotes
|
hypoglycemia
(
J:64878
)
• in oral glucose tolerance tests heterozygotes show hypoglycemia relative to wildtype controls, but not as severe as in homozygotes
|
endocrine/exocrine glands
• the pancreatic insulin content of 8 week old heterozygotes is approximately 118 ug/g, lower than the 171 mg/g in wildtype controls and higher than the 34 mg/g in homozygotes
|
integument