Analysis Tools
behavior/neurological
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• unusual whisker trimming and hair nibbling is observed in >90% of cages containing female homozygotes as young as 1.5-2 months of age
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• unusual whisker trimming and hair nibbling is observed in >90% of cages containing female homozygotes as young as 1.5-2 months of age
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• occasionally, homozygotes display epileptic seizures in response to moderate stress (e.g. handling just after awakening)
• although the actual sequence of events is variable among different episodes, one or several of the following may be observed: foamy saliva around the oral region, squeaking prior to falling on the side, a brief period of intense convulsions, curled up tail, folding back of limbs if raised by the tail, complete akinesia for up to 5 min, and polyuria
• recovery from seizures is progressive and takes several minutes
• most affected homozygotes displaying one or more seizures are female; however, a few males are also affected
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• homozygotes, esp. females, are prone to spontaneous epileptic seizures
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nervous system
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• occasionally, homozygotes display epileptic seizures in response to moderate stress (e.g. handling just after awakening)
• although the actual sequence of events is variable among different episodes, one or several of the following may be observed: foamy saliva around the oral region, squeaking prior to falling on the side, a brief period of intense convulsions, curled up tail, folding back of limbs if raised by the tail, complete akinesia for up to 5 min, and polyuria
• recovery from seizures is progressive and takes several minutes
• most affected homozygotes displaying one or more seizures are female; however, a few males are also affected
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• homozygotes, esp. females, are prone to spontaneous epileptic seizures
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