mortality/aging
• 40% survive at least until 6 weeks of age
|
• 60% die between 8 and 30 days of age
|
craniofacial
malocclusion
(
J:48123
)
• low body weight attributed in part to dental occlusion
|
digestive/alimentary system
• low body weight attributed in part to partial colon obstruction
|
endocrine/exocrine glands
small ovary
(
J:48123
)
• characteristic of 87% of XX mice
|
growth/size/body
malocclusion
(
J:48123
)
• low body weight attributed in part to dental occlusion
|
• a few days after birth pups weigh 26% of littermate control weight
|
reproductive system
small ovary
(
J:48123
)
• characteristic of 87% of XX mice
|
• 50% of XY mice had both ovarian and testicular tissue
|
• 50% of XY mice had only ovaries
|
skeleton
malocclusion
(
J:48123
)
• low body weight attributed in part to dental occlusion
|
• homeotic transformations are seen over the entire axis; six rather than seven vertebrosternal ribs develop,fusion of exoccipital to proatlas with first cervical vertebra becoming equivalent to C2, C6 or C7 becomes first thoracic vertebra,lumbar vertebra L5 or L6 becomes the first sacral vertebra
|