Phenotypes associated with this allele

• Allele Symbol: Csn2^tm1Psim
• Allele Name: targeted mutation 1, Paul Simons
• Allele ID: MGI:2182074
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Csn2^tm1Psim/Csn2^tm1Psim	involves: 129P2/OlaHsd * MF1	MGI:3696685

Genotype
MGI:3696685

hm1

• Allelic Composition: Csn2^tm1Psim/Csn2^tm1Psim
• Genetic Background: involves: 129P2/OlaHsd * MF1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal milk composition ( J:18947 )

♀ • less milk protein in milk from homozygous mothers

♀ • casein micelles are smaller than normal and totally lack beta-casein

integument

abnormal milk composition ( J:18947 )

♀ • less milk protein in milk from homozygous mothers

♀ • casein micelles are smaller than normal and totally lack beta-casein

cellular

maternal effect ( J:18947 )

• growth rate of pups nursed by homozygous mothers is significantly slower than normal as a result of deficiencies in milk composition