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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(SOD1*G85R)74Dwc
transgene insertion 74, Don W Cleveland
MGI:2182172
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(SOD1*G85R)74Dwc/? Not Specified MGI:3832567


Genotype
MGI:3832567
tg1
Allelic
Composition
Tg(SOD1*G85R)74Dwc/?
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• weakened grip strength in one hindlimb first observed by 12-14 months and spreading rapidly to other limbs
• complete paralysis occurs two weeks after onset of weakened grip strength
• hindlimb paralysis is first observed at 12-14 months

muscle

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
amyotrophic lateral sclerosis type 1 DOID:0060193 OMIM:105400
J:77600





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory