Phenotypes associated with this allele

• Allele Symbol: Ncam1^tm1Mag
• Allele Name: targeted mutation 1, Terry Magnuson
• Allele ID: MGI:2182406
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ncam1^tm1Mag/Ncam1^tm1Mag	involves: 129S2/SvPas * CF-1	MGI:2182569

Genotype
MGI:2182569

hm1

• Allelic Composition: Ncam1^tm1Mag/Ncam1^tm1Mag
• Genetic Background: involves: 129S2/SvPas * CF-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

shortened circadian behavior period ( J:96708 )

• the circadian period in DD conditions is significantly shorter in mutants, 23.50 hours compared to 23.90 hours in wild-type littermates

• the duration of the active period increased under DD conditions so that after 3 weeks rhythmicity is lost

vision/eye

abnormal retina morphology ( J:37891 )

• appearance of cell bodies in the plexiform layers

nervous system

abnormal hippocampus pyramidal cell layer ( J:37891 )

• abnormal pyramidal layer; dispersed and often split

abnormal olfactory bulb morphology ( J:37891 )

• reduced granule cell number, disorganized granule cell layer and abnormal migration of granule cell precursors

small olfactory bulb ( J:37891 )

• approximately half the size of heterozygous littermates

abnormal cerebellum morphology ( J:37891 )

• reduced length of lobule IV