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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dsptm2Efu
targeted mutation 2, Elaine Fuchs
MGI:2182575
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dsptm2Efu/Dsptm2Efu involves: 129S1/Sv * 129X1/SvJ MGI:2652091


Genotype
MGI:2652091
hm1
Allelic
Composition
Dsptm2Efu/Dsptm2Efu
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dsptm2Efu mutation (0 available); any Dsp mutation (136 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• by E6.5; followed by reduction in adherens junctions and morphological signs of cellular degeneration

embryo
• defects in cell-cell adhesion results in partial delamination of the endodermal layer; disruptions are also seen in the ectodermal layer
• defects in cell-cell adhesion results in partial delamination of the endodermal layer; disruptions are also seen in the ectodermal layer
• mutant embryos are smaller than littermates
• absence of desmosome
• defects in egg cylinder elongation

growth/size/body
• mutant embryos are smaller than littermates





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory