About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dsptm2Efu
targeted mutation 2, Elaine Fuchs
MGI:2182575
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dsptm2Efu/Dsptm2Efu involves: 129S1/Sv * 129X1/SvJ MGI:2652091


Genotype
MGI:2652091
hm1
Allelic
Composition
Dsptm2Efu/Dsptm2Efu
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dsptm2Efu mutation (0 available); any Dsp mutation (136 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• by E6.5; followed by reduction in adherens junctions and morphological signs of cellular degeneration

embryo
• defects in cell-cell adhesion results in partial delamination of the endodermal layer; disruptions are also seen in the ectodermal layer
• defects in cell-cell adhesion results in partial delamination of the endodermal layer; disruptions are also seen in the ectodermal layer
• mutant embryos are smaller than littermates
• absence of desmosome
• defects in egg cylinder elongation

growth/size/body
• mutant embryos are smaller than littermates





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory