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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
H1f0tm1Ais
targeted mutation 1, Art I Skoultchi
MGI:2182779
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
H1f0tm1Ais/H1f0tm1Ais involves: 129P2/OlaHsd * C57BL/6 MGI:3844493
cx2
H1f0tm1Ais/H1f0tm1Ais
H1f2tm2Ais/H1f2tm2Ais
H1f3tm2Ais/H1f3tm2Ais
H1f4tm2Ais/H1f4tm2Ais
involves: 129/Sv * C57BL/6 * SJL MGI:2674074
cx3
H1f0tm1Ais/H1f0tm1Ais
H1f2tm2Ais/H1f2tm2Ais
H1f4tm2Ais/H1f4tm2Ais
involves: 129/Sv * C57BL/6 * SJL MGI:2674076
cx4
H1f0tm1Ais/H1f0tm1Ais
H1f2tm1Ais/H1f2tm1Ais
involves: 129P2/OlaHsd * C57BL MGI:3844478
cx5
H1f0tm1Ais/H1f0tm1Ais
H1f4tm1Ais/H1f4tm1Ais
involves: 129P2/OlaHsd * C57BL/6 MGI:3844467
cx6
H1f0tm1Ais/H1f0tm1Ais
H1f3tm1Ais/H1f3tm1Ais
involves: 129P2/OlaHsd * C57BL/6 MGI:3844473


Genotype
MGI:3844493
hm1
Allelic
Composition
H1f0tm1Ais/H1f0tm1Ais
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0tm1Ais mutation (0 available); any H1f0 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• viable, fertile and overtly normal
• no apparent anatomic or histologic abnormalities
• no defects in cell division patterns




Genotype
MGI:2674074
cx2
Allelic
Composition
H1f0tm1Ais/H1f0tm1Ais
H1f2tm2Ais/H1f2tm2Ais
H1f3tm2Ais/H1f3tm2Ais
H1f4tm2Ais/H1f4tm2Ais
Genetic
Background
involves: 129/Sv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0tm1Ais mutation (0 available); any H1f0 mutation (13 available)
H1f2tm2Ais mutation (0 available); any H1f2 mutation (16 available)
H1f3tm2Ais mutation (0 available); any H1f3 mutation (8 available)
H1f4tm2Ais mutation (0 available); any H1f4 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no homozygotes are born

embryo
• E9.5 embryos are severely retarded and abnormal




Genotype
MGI:2674076
cx3
Allelic
Composition
H1f0tm1Ais/H1f0tm1Ais
H1f2tm2Ais/H1f2tm2Ais
H1f4tm2Ais/H1f4tm2Ais
Genetic
Background
involves: 129/Sv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0tm1Ais mutation (0 available); any H1f0 mutation (13 available)
H1f2tm2Ais mutation (0 available); any H1f2 mutation (16 available)
H1f4tm2Ais mutation (0 available); any H1f4 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygotes are under represented in litters at birth

growth/size/body
• mice are much smaller at birth and as adults

immune system
• histologically normal however

reproductive system
• both male and female mutants are fertile when crossed to wild-type mice but display reduced fertility when crossed to one another

hematopoietic system
• histologically normal however

endocrine/exocrine glands
• histologically normal however




Genotype
MGI:3844478
cx4
Allelic
Composition
H1f0tm1Ais/H1f0tm1Ais
H1f2tm1Ais/H1f2tm1Ais
Genetic
Background
involves: 129P2/OlaHsd * C57BL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0tm1Ais mutation (0 available); any H1f0 mutation (13 available)
H1f2tm1Ais mutation (0 available); any H1f2 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:3844467
cx5
Allelic
Composition
H1f0tm1Ais/H1f0tm1Ais
H1f4tm1Ais/H1f4tm1Ais
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0tm1Ais mutation (0 available); any H1f0 mutation (13 available)
H1f4tm1Ais mutation (0 available); any H1f4 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:3844473
cx6
Allelic
Composition
H1f0tm1Ais/H1f0tm1Ais
H1f3tm1Ais/H1f3tm1Ais
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0tm1Ais mutation (0 available); any H1f0 mutation (13 available)
H1f3tm1Ais mutation (0 available); any H1f3 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory