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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ppef2tm1Nat
targeted mutation 1, Jeremy Nathans
MGI:2182812
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ppef2tm1Nat/Ppef2tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3040620
cx2
Ppef1tm1Nat/Ppef1tm1Nat
Ppef2tm1Nat/Ppef2tm1Nat
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3040621
cx3
Ppef1tm1Nat/Y
Ppef2tm1Nat/Ppef2tm1Nat
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3040622


Genotype
MGI:3040620
hm1
Allelic
Composition
Ppef2tm1Nat/Ppef2tm1Nat
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppef2tm1Nat mutation (0 available); any Ppef2 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
N
• normal rod function
• normal retinal histology up to 1 year of age
• no retinal degeneration for one year, no later time points measured

normal phenotype
• authors state mice are viable, fertile, with no overt abnormalities




Genotype
MGI:3040621
cx2
Allelic
Composition
Ppef1tm1Nat/Ppef1tm1Nat
Ppef2tm1Nat/Ppef2tm1Nat
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppef1tm1Nat mutation (0 available); any Ppef1 mutation (4 available)
Ppef2tm1Nat mutation (0 available); any Ppef2 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
N
• normal rod function
• normal retinal histology at 3 months
• no retinal degeneration for 3 months, no later time points measured

normal phenotype
• authors state mice are viable, fertile, with no overt abnormalities




Genotype
MGI:3040622
cx3
Allelic
Composition
Ppef1tm1Nat/Y
Ppef2tm1Nat/Ppef2tm1Nat
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppef1tm1Nat mutation (0 available); any Ppef1 mutation (4 available)
Ppef2tm1Nat mutation (0 available); any Ppef2 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
N
• normal rod function
• normal retinal histology at 3 months of age
• no retinal degeneration for 3 months, no later time points measured

normal phenotype
• authors state mice are viable, fertile, with no overt abnormalities





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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory