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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Evx1tm1.1Gld
targeted mutation 1.1, Martyn Goulding
MGI:2182858
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Evx1tm1.1Gld/Evx1tm1.1Gld involves: 129S/SvEv * C57BL/6 MGI:2183152


Genotype
MGI:2183152
hm1
Allelic
Composition
Evx1tm1.1Gld/Evx1tm1.1Gld
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Evx1tm1.1Gld mutation (0 available); any Evx1 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• normal alternate right left pattern of motor activity in L2 and L5 motor roots is preserved
• abnormal interneurons: V0 interneurons adopt a V1 interneuron cell fate
• abnormal axonal projections: V0 interneurons fail to project commissural axons; instead they project ipsilateral axonal projections similar to V1 interneurons





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory