About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ucp3tm1Brnd
targeted mutation 1, Martin D Brand
MGI:2183204
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ucp3tm1Brnd/Ucp3tm1Brnd B6.Cg-Ucp3tm1Brnd MGI:3852052
hm2
 		Ucp3tm1Brnd/Ucp3tm1Brnd Not Specified MGI:3852053


Genotype
MGI:3852052
hm1
Allelic
Composition		 Ucp3tm1Brnd/Ucp3tm1Brnd
Genetic
Background		 B6.Cg-Ucp3tm1Brnd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ucp3tm1Brnd mutation (0 available); any Ucp3 mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal mitochondrial physiology ( J:73905 )
• skeletal muscle mitochondria proton conductance is insensitive to superoxide treatment unlike wild-type mitochondria




Genotype
MGI:3852053
hm2
Allelic
Composition		 Ucp3tm1Brnd/Ucp3tm1Brnd
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ucp3tm1Brnd mutation (0 available); any Ucp3 mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased skeletal muscle triglyceride level ( J:106901 )
• when fed a high-fat diet, intramuscular triglyceride levels are lower than in similarly treated wild-type mice

muscle
decreased skeletal muscle triglyceride level ( J:106901 )
• when fed a high-fat diet, intramuscular triglyceride levels are lower than in similarly treated wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory