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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cebpatm1.1(Cebpb)Ylee
targeted mutation 1.1, Ying-Hue Lee
MGI:2183333
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1(Cebpb)Ylee involves: 129X1/SvJ * C57BL/6 * FVB/N MGI:3809478
ht2
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1Gonz involves: 129X1/SvJ * C57BL/6 * FVB/N MGI:3809479


Genotype
MGI:3809478
hm1
Allelic
Composition
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1(Cebpb)Ylee
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cebpatm1.1(Cebpb)Ylee mutation (0 available); any Cebpa mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• brown adipose tissue is more vacuolated than in wild-type mice
• adipocytes are reduced in size and exhibit reduced lipid accumulation compared to in wild-type mice
• white adipose tissue is reduced and yellow compared to in wild-type mice

homeostasis/metabolism
N
• unlike in Cebpa null mice, normal serum glucose and lipid levels

behavior/neurological
• mice consume 9% more food than wild-type mice

hematopoietic system
• mice exhibit decreased hemolytic activity compared to wild-type mice

growth/size/body
N
• unlike in Cebpa null mice, growth is normal

immune system
N
• unlike in Cebpa null mice, acute phase response to LPS is normal

reproductive system
N
• mice are fertile




Genotype
MGI:3809479
ht2
Allelic
Composition
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1Gonz
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cebpatm1.1(Cebpb)Ylee mutation (0 available); any Cebpa mutation (19 available)
Cebpatm1.1Gonz mutation (0 available); any Cebpa mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• white adipose tissue is reduced and yellow compared to in wild-type mice





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory