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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mxd3tm1Rne
targeted mutation 1, Robert N Eisenman
MGI:2183621
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mxd3tm1Rne/Mxd3tm1Rne either: 129S4/SvJaeSor or (involves: 129S4/SvJaeSor * C57BL/6J) MGI:3580913


Genotype
MGI:3580913
hm1
Allelic
Composition		 Mxd3tm1Rne/Mxd3tm1Rne
Genetic
Background		 either: 129S4/SvJaeSor or (involves: 129S4/SvJaeSor * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mxd3tm1Rne mutation (0 available); any Mxd3 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased cellular sensitivity to gamma-irradiation ( J:77649 )
• a 10% increase in the number of dead thymocytes 24 or 48 hours following gamma irradiation at 200, 500 and 1000 rads
• neural progenitor cells also demonstrated increased sensitivity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory