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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fgf1tm1Bas
targeted mutation 1, Claudio Basilico
MGI:2383991
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fgf1tm1Bas/Fgf1tm1Bas involves: 129P2/OlaHsd MGI:3663307
cx2
 		Fgf1tm1Bas/Fgf1tm1Bas
Fgf2tm1Bas/Fgf2tm1Bas 		involves: 129P2/OlaHsd * C57BL/6 MGI:3663306


Genotype
MGI:3663307
hm1
Allelic
Composition		 Fgf1tm1Bas/Fgf1tm1Bas
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf1tm1Bas mutation (0 available); any Fgf1 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:60597 )
• animals are of normal appearance and fertility
• brain architecture and wound healing are both normal
• mice age normally




Genotype
MGI:3663306
cx2
Allelic
Composition		 Fgf1tm1Bas/Fgf1tm1Bas
Fgf2tm1Bas/Fgf2tm1Bas
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf1tm1Bas mutation (0 available); any Fgf1 mutation (44 available)
Fgf2tm1Bas mutation (0 available); any Fgf2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neocortex morphology ( J:60597 )
• thickening of the neocortex and decreased neuronal cell density is seen which is similar to that in homozygous Fgf2tm1Bas mice

hematopoietic system
abnormal bone marrow cell morphology/development ( J:60597 )
• deficiency of myeloid precursors as seen in homozygous Fgf2tm1Bas mice

homeostasis/metabolism
delayed wound healing ( J:60597 )
• delayed wound healing similar to that in homozygous Fgf2tm1Bas mice is seen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory