Phenotypes associated with this allele

• Allele Symbol: Tg(UPII-SV40T)9Xrw
• Allele Name: transgene insertion 9, Xue-Ru Wu
• Allele ID: MGI:2384609
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(UPII-SV40T)9Xrw/0	involves: FVB/N	MGI:5141748

Genotype
MGI:5141748

tg1

• Allelic Composition: Tg(UPII-SV40T)9Xrw/0
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased urinary bladder carcinoma incidence ( J:56305 )

• although mutants appear outwardly healthy at 5-8 months of age, they show features of bladder carcinoma in situ (CIS), including moderate-to-severe urothelial atypia with marked nuclear pleomophism such as giant nuclei and abundant mitotic figures

• CIS lesions do not progress to transitional cell carcinoma (TCC) by 8 months of age

renal/urinary system

increased urinary bladder carcinoma incidence ( J:56305 )

• although mutants appear outwardly healthy at 5-8 months of age, they show features of bladder carcinoma in situ (CIS), including moderate-to-severe urothelial atypia with marked nuclear pleomophism such as giant nuclei and abundant mitotic figures

• CIS lesions do not progress to transitional cell carcinoma (TCC) by 8 months of age