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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gfaptm3Ito
targeted mutation 3, Shigeyoshi Itohara
MGI:2384720
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gfaptm3Ito/Gfaptm3Ito either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) MGI:3790657


Genotype
MGI:3790657
hm1
Allelic
Composition		 Gfaptm3Ito/Gfaptm3Ito
Genetic
Background		 either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfaptm3Ito mutation (1 available); any Gfap mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal astrocyte morphology ( J:78341 )
• fewer astrocytes with glial fibrillary acidic protein (GFAP)-labeled processes are observed in some brain areas compared to wild-type
• cellular processes expressing GFAP are short relative to wild-type astrocytes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory