All Phenotypes Epor<tm1.2Jtp> MGI Mouse

vision/eye phenotype ( J:291641 )

N	• normal visual acuity under photopic and scotopic conditions at age 4, 6 and 8 weeks • normal a- and b-wave amplitudes under photopic and scotopic conditions at age 8 weeks • normal number of cone nuclei in central and peripheral retina at age 8 weeks • normal number of rod bipolar cells

decreased amacrine cell number ( J:291641 )

• in central and peripheral retina at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7

decreased retina rod cell number ( J:291641 )

• normal number of rod nuclei in central and peripheral retina at age 8 weeks

• reduced number of rod nuclei in peripheral retina at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7

increased amacrine cell number ( J:291641 )

• in central and peripheral retina at age 8 weeks

thin retina inner plexiform layer ( J:291641 )

• reduced central thickness at age 8 weeks; no change after oxygen-induced injury and repair (OIR) at age P7

• thicker peripheral OPL at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7

thin retina outer plexiform layer ( J:291641 )

• further reduced central thickness at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7

• reduced central thickness at age 8 weeks

decreased total retina thickness ( J:291641 )

• reduced central total retina thickness

decreased a-wave amplitude ( J:291641 )

• under scotopic conditions at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7

• normal a-wave amplitude under photopic conditions at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7

decreased b-wave amplitude ( J:291641 )

• normal b-wave amplitude under photopic conditions at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7

• reduced oscillatory potential amplitude under scotopic conditions at age 8 weeks after oxygen-induced injury and repair (OIR) at age P7