Analysis Tools|
Allele Symbol Allele Name Allele ID |
Raratm3.1Ipc targeted mutation 3.1, Pierre Chambon MGI:2386107 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• testicular degeneration manifested by the sloughing of immature germ cells in the lumen of seminiferous tubules
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• testicular degeneration manifested by the sloughing of immature germ cells in the lumen of seminiferous tubules
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• there is about a 3-fold increase in the number of Ki67-positive hepatocytes in 14 week old mice
• this number of Ki67-positive hepatocytes 40% less than the number found in age-matched mice that are homozygous null for Trim24 but homozygous wild-type for Rara
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| N |
• no liver tumors are found in mice between 12 and 15 months of age compared to 70% liver tumor incidence in age-matched mice that are homozygous null for Trim24 but homozygous wild-type for Rara
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• there is about a 3-fold increase in the number of Ki67-positive hepatocytes in 14 week old mice
• this number of Ki67-positive hepatocytes 40% less than the number found in age-matched mice that are homozygous null for Trim24 but homozygous wild-type for Rara
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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