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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Igfbp2tm1Jep
targeted mutation 1, John E Pintar
MGI:2386117
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Igfbp2tm1Jep/Igfbp2tm1Jep either: (involves: 129P1/ReJ * 129S/SvEv) or (involves: 129S/SvEv * C57BL/6) MGI:3603596


Genotype
MGI:3603596
hm1
Allelic
Composition		 Igfbp2tm1Jep/Igfbp2tm1Jep
Genetic
Background		 either: (involves: 129P1/ReJ * 129S/SvEv) or (involves: 129S/SvEv * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igfbp2tm1Jep mutation (0 available); any Igfbp2 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
small spleen ( J:64338 )
• normal size at 12 days of age but proportionately smaller as mice age
• contains reduced numbers of lymphocytes

liver/biliary system

cardiovascular system
decreased heart weight ( J:64338 )
• decreased heart weight to body weight ratio

renal/urinary system
decreased kidney weight ( J:64338 )
• decreased kidney weight to body weight ratio

hematopoietic system
small spleen ( J:64338 )
• normal size at 12 days of age but proportionately smaller as mice age
• contains reduced numbers of lymphocytes

growth/size/body
increased liver weight ( J:64338 )




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory