Phenotypes associated with this allele

• Allele Symbol: H2-Oa^tm1Dma
• Allele Name: targeted mutation 1, Daniel M Altmann
• Allele ID: MGI:2386294
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	H2-Oa^tm1Dma/H2-Oa^tm1Dma	involves: 129/Sv * C57BL/6	MGI:3844866

Genotype
MGI:3844866

hm1

• Allelic Composition: H2-Oa^tm1Dma/H2-Oa^tm1Dma
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased CD4-positive, alpha-beta T cell number ( J:65235 )

• the mean proportion of CD4 single-positive thymocytes changed from 7.6% in wild-type mice to 9.8% in these mice

abnormal antigen presentation via MHC class II ( J:65235 )

• the array of endogenous peptides presented by MHC class II in the spleen is altered

hematopoietic system

increased CD4-positive, alpha-beta T cell number ( J:65235 )

• the mean proportion of CD4 single-positive thymocytes changed from 7.6% in wild-type mice to 9.8% in these mice