Analysis Tools
mortality/aging
|
• appear normal for 4-6 days after birth
• mice die within 2 days of the onset of respiratory distress which occurs around day 6-12
• survival can be prolonged by draining fluid in thorax but only to about 21 days of age
|
growth/size/body
|
• smaller than littermate controls by day 6-8
|
respiratory system
chylothorax
(
J:63038
)
|
• high concentrations of both triglycerides and cholesterol
• 90% of cells in fluid collected in the thoracic cavity were lymphocytes
|
|
• all mice show signs of respiratory distress between 6 and 12 days of age
|
immune system
|
• edema and lymphocytes sometimes seen in tissue surrounding thoracic duct
|
cardiovascular system
|
• edema and lymphocytes sometimes seen in tissue surrounding thoracic duct
|
homeostasis/metabolism
chylothorax
(
J:63038
)
|
• high concentrations of both triglycerides and cholesterol
• 90% of cells in fluid collected in the thoracic cavity were lymphocytes
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| congenital chylothorax | DOID:0060646 |
OMIM:603523 |
J:63038 | |
