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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Myh10tm1Rsad
targeted mutation 1, Robert S Adelstein
MGI:2386439
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Myh10tm1Rsad/Myh10tm1Rsad involves: 129S4/SvJae MGI:3052315
ht2
 		Myh10tm1Rsad/Myh10tm2Rsad involves: 129S4/SvJae MGI:3052317


Genotype
MGI:3052315
hm1
Allelic
Composition		 Myh10tm1Rsad/Myh10tm1Rsad
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh10tm1Rsad mutation (1 available); any Myh10 mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiac hypertrophy ( J:92230 )
• mutants develop postnatal cardiac hypertrophy however at E13.5 no increase in the number of binucleated cardiac myocytes or in the size of cardiac myocytes is seen

growth/size/body
cardiac hypertrophy ( J:92230 )
• mutants develop postnatal cardiac hypertrophy however at E13.5 no increase in the number of binucleated cardiac myocytes or in the size of cardiac myocytes is seen




Genotype
MGI:3052317
ht2
Allelic
Composition		 Myh10tm1Rsad/Myh10tm2Rsad
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh10tm1Rsad mutation (1 available); any Myh10 mutation (95 available)
Myh10tm2Rsad mutation (1 available); any Myh10 mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiac hypertrophy ( J:92230 )
• mutants develop postnatal cardiac hypertrophy however at E13.5 no increase in the number of binucleated cardiac myocytes or in the size of cardiac myocytes is seen

growth/size/body
cardiac hypertrophy ( J:92230 )
• mutants develop postnatal cardiac hypertrophy however at E13.5 no increase in the number of binucleated cardiac myocytes or in the size of cardiac myocytes is seen




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory