All Phenotypes Atxn1<tm2Zuk> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Atxn1^tm2Zuk
targeted mutation 2, Martin M Matzuk
MGI:2386669

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atxn1^tm2Zuk/Atxn1^tm2Zuk	either: (involves: 129S/SvEv) or (involves: 129S7/SvEvBrd * C57BL/6)	MGI:3841064

Allelic Composition	Atxn1^tm2Zuk/Atxn1^tm2Zuk
Genetic Background	either: (involves: 129S/SvEv) or (involves: 129S7/SvEvBrd * C57BL/6)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atxn1^tm2Zuk mutation (0 available); any Atxn1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired coordination ( J:61398 )

• rotarod performance deteriorates with age

• normal at 3 months, slightly deficient at 6 months, and significantly poor a 9 months

• Background Sensitivity: performance is somewhat better on a "pure" 129/SvEv background

• no ataxia or other gross abnormalities up to 18 months of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24