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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pdha1tm1.1Ptl
targeted mutation 1.1, Mulchand S Patel
MGI:2386704
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pdha1tm1.1Ptl/Pdha1tm1.1Ptl involves: 129P2/OlaHsd * FVB/N MGI:3843814
ot2
 		Pdha1tm1.1Ptl/Y involves: 129P2/OlaHsd * FVB/N MGI:3843815


Genotype
MGI:3843814
hm1
Allelic
Composition		 Pdha1tm1.1Ptl/Pdha1tm1.1Ptl
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdha1tm1.1Ptl mutation (0 available); any Pdha1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:74192 )
• by E12.5 mice show increased signs of resorption

embryo
embryonic growth retardation ( J:74192 )
• at E9.5, mice exhibit developmental delay of 1 day compared with wild-type mice

growth/size/body
embryonic growth retardation ( J:74192 )
• at E9.5, mice exhibit developmental delay of 1 day compared with wild-type mice
decreased embryo size ( J:74192 )
• at E9.5




Genotype
MGI:3843815
ot2
Allelic
Composition		 Pdha1tm1.1Ptl/Y
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdha1tm1.1Ptl mutation (0 available); any Pdha1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:74192 )
• by E12.5 mice show increased signs of resorption

embryo
embryonic growth retardation ( J:74192 )
• at E9.5, mice exhibit developmental delay of 1 day compared with wild-type mice

growth/size/body
embryonic growth retardation ( J:74192 )
• at E9.5, mice exhibit developmental delay of 1 day compared with wild-type mice
decreased embryo size ( J:74192 )
• at E9.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory