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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lxl2
luxate-like 2
MGI:2386941
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lxl2/Lxl2 B6;AKR-Lxl2/GrsrJ MGI:2677886
ht2
 		Lxl2/Lxl2+ B6;AKR-Lxl2/GrsrJ MGI:2677885


Genotype
MGI:2677886
hm1
Allelic
Composition		 Lxl2/Lxl2
Genetic
Background		 B6;AKR-Lxl2/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lxl2 mutation (1 available); any Lxl2 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:79041 )
• it is believed that homozygous Lxl2 mutants die in utero because a homozygous mutant has never been born




Genotype
MGI:2677885
ht2
Allelic
Composition		 Lxl2/Lxl2+
Genetic
Background		 B6;AKR-Lxl2/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lxl2 mutation (1 available); any Lxl2 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Lxl2/Lxl2+ whold body xray

limbs/digits/tail
abnormal limb morphology ( J:79041 )
• females have all four limbs at odd angles to the body
• rear legs of females are oriented/twisted backward
polydactyly ( J:79041 )
• females have extra digits on all four feet




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory